Compound Directory

BPC 157

A reviewed compound profile linking technical facts, evidence summaries, limitations, studies, trials, COAs, and related products.

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PubChem compound record for BPC-157

National Center for Biotechnology Information · PubChem

unknown
Open source record

pubmed

Multifunctionality and Possible Medical Application of the BPC 157 Peptide-Literature and Patent Review.

Michalina Józwiak, Marta Bauer, Wojciech Kamysz, Patrycja Kleczkowska · Pharmaceuticals (Basel, Switzerland) · 2025

Preclinical animal study · Animal model; verify the species in the source

Open source record

pubmed

Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review.

Nikhil Vasireddi, Henrik Hahamyan, Michael J Salata, Michael Karns, Jacob G Calcei, James E Voos, John M Apostolakos · HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2026

Systematic review or meta-analysis · Human participants; verify the population in the source

Open source record

pubmed

Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing.

Daniel Gwyer, Nicholas M Wragg, Samantha L Wilson · Cell and tissue research · 2019

Preclinical animal study · Animal model; verify the species in the source

Open source record

pubmed

Stable Gastric Pentadecapeptide BPC 157 and Wound Healing.

Sven Seiwerth, Marija Milavic, Jaksa Vukojevic, Slaven Gojkovic, Ivan Krezic, Lovorka Batelja Vuletic, Katarina Horvat Pavlov, Andrea Petrovic, Suncana Sikiric, Hrvoje Vranes, Andreja Prtoric, Helena Zizek, Tajana Durasin, Ivan Dobric, Mario Staresinic, Sanja Strbe, Mario Knezevic, Marija Sola, Antonio Kokot, Marko Sever, Eva Lovric, Anita Skrtic, Alenka Boban Blagaic, Predrag Sikiric · Frontiers in pharmacology · 2021

Preclinical animal study · Animal model; verify the species in the source

Open source record

Verified COA records

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Registered trials

NCT07437547 · RECRUITING

BPC 157 for Acute Hamstring Muscle Strain Repair

This randomized, double-blind, placebo-controlled Phase 2 study evaluates whether pentadecapeptide BPC 157 (BPC-157), an investigational peptide, can speed structural healing and functional recovery after an acute grade II hamstring muscle strain. Participants will receive BPC 157 or placebo for 14 days in addition to a standardized rehabilitation program. The co-primary endpoints are time to return to unrestricted sport and change in MRI-assessed injury volume at Day 14.

Outcomes: Time to return to unrestricted sport participation (days) · Change from baseline to Day 14 in MRI-assessed hamstring injury volume (cm^3), measured by blinded central radiology review. · Change in pain during activity on a 0-10 Numeric Rating Scale (NRS; 0 = no pain, 10 = worst pain). · Hamstring strength limb symmetry index (LSI) by isokinetic dynamometry · Change in Lower Extremity Functional Scale (LEFS; 0-80, higher scores indicate better function)

PHASE2

NCT07752381 · COMPLETED

A Clinical Trial to Evaluate the Effects of Peptide Gummies on Markers of Inflammation, Physical Performance, and Recovery

This study will evaluate the effects of Parlay Recover peptide gummies (containing Body Protection Compound BPC-157) on markers of inflammation, physical performance, and recovery in physically active adults. Over an 8-week period, 40 participants will consume two gummies daily and complete questionnaires at Baseline, Week 2, Week 4, Week 6, and Week 8, as well as undergo blood testing at Baseline and Week 8. The primary objective is to examine changes in inflammatory biomarkers (hs-CRP and IL-6) as measured by blood testing. Secondary objectives include evaluating participants' self-reported perceptions of the product's effects on physical performance and recovery, including aching, stiffness, function, and recovery of muscles and joints.

Outcomes: Change in High-Sensitivity C-Reactive Protein (hs-CRP) · Change in Interleukin-6 (IL-6) · Change in Self-Reported Swelling · Change in Self-Reported Aching · Change in Self-Reported Stiffness · Change in Self-Reported Muscle Function · Change in Self-Reported Recovery

NA

NCT02637284 · UNKNOWN

PCO-02 - Safety and Pharmacokinetics Trial

Phase I clinical trial in healthy volunteers to study safety and pharmacokinetics of BPC-157, a pentadecapeptide from gastric source.

Outcomes: Adverse events · Maximum plasma concentration · Time to maximum plasma concentration · Area under the curve · Elimination half life

PHASE1